It’s been many years since I read that SQL databases should use an NTFS volume formatted with at 64KB file allocation unit size (block size). So long that I didn’t remember why or if it is still considered best/good practice. It appears that it is according to Microsoft and the foremost authority on SQL with ConfigMgr.
Microsoft recommends this for User Databases and the TempDB: https://docs.microsoft.com/en-gb/azure/virtual-machines/virtual-machines-windows-sql-performance?toc=%2fazure%2fvirtual-machines%2fwindows%2ftoc.json
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